Thiobarbital

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Thiobarbital
Identifiers
  • 5,5-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
JSmol)
  • O=C1NC(=S)NC(=O)C1(CC)CC
  • InChI=1S/C8H12N2O2S/c1-3-8(4-2)5(11)9-7(13)10-6(8)12/h3-4H2,1-2H3,(H2,9,10,11,12,13) checkY
  • Key:QGVNJRROSLYGKF-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Thiobarbital is a drug which is a barbiturate derivative. It is the thiobarbiturate analogue of barbital.

Synthesis

Thiobarbital synthesis:[1][2]

It is of note that although the drug can be prepared by the above route (cf e.g. thialbarbital), reaction of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.

References