ORG-21465

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ORG-21465
Clinical data
Other names2β-(2,2-Dimethyl-4-morpholinyl)-3α-hydroxy-11,20-dioxo-5α-pregnan-21-yl methanesulfonate
Identifiers
  • [2-[(2S,3S,5S,8S,9S,10S,13S,14S,17S)-2-(2,2-dimethylmorpholin-4-yl)-3-hydroxy-10,13-dimethyl-11-oxo-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl]methanesulfonate
JSmol)
  • O=S(=O)(OCC(=O)[C@H]5CC[C@@H]1[C@]5(C)CC(=O)[C@H]3[C@H]1CC[C@H]4C[C@H](O)[C@@H](N2CC(OCC2)(C)C)C[C@]34C)C
  • InChI=1S/C28H45NO7S/c1-26(2)16-29(10-11-35-26)21-13-27(3)17(12-22(21)30)6-7-18-19-8-9-20(24(32)15-36-37(5,33)34)28(19,4)14-23(31)25(18)27/h17-22,25,30H,6-16H2,1-5H3/t17-,18-,19-,20+,21-,22-,25+,27-,28-/m0/s1
  • Key:SUCBEQDWLIEMEH-JDOQEMNXSA-N
  (verify)

ORG-21465 is a synthetic

althesin and allopregnanolone, which despite its superior properties in some respects has not proved to offer enough advantages to be accepted into clinical use.[1][2]

Chemistry

See also: List of neurosteroids

See also

References

  1. PMID 9389254
    .
  2. PMID 18175096
    .
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