NS-11394

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NS-11394
Identifiers
  • 2-(3-[5-(2-hydroxypropan-2-yl)benzimidazol-1-yl]phenyl)benzonitrile
JSmol)
SMILES
  • N#Cc2ccccc2-c(ccc3)cc3-n1cnc(c4)c1ccc4C(C)(C)O
  • InChI=1S/C23H19N3O/c1-23(2,27)18-10-11-22-21(13-18)25-15-26(22)19-8-5-7-16(12-19)20-9-4-3-6-17(20)14-24/h3-13,15,27H,1-2H3 ☒N
  • Key:HLKYSQGBIIIQJN-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

NS-11394 is a drug which acts as a subtype-selective

GABAA receptors, with selectivity for the α3 and α5 subtypes.[1][2] It has been researched as an analgesic for use in chronic or neuropathic pain.[3]

References

  1. S2CID 36490884
    .
  2. S2CID 206499795
    .
  3. PMID 19729210
    .
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