Minoxidil sulfate
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| Other names | Minoxidil sulphate; Minoxidil sulfate ester; Minoxidil sulphate ester; Minoxidil N-O-sulfate; Minoxidil N-O-sulphate; U-58838 |
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Minoxidil sulfate, also known as minoxidil sulfate ester or minoxidil N-O-sulfate, is an
hypertrichotic (hair growth-promoting) effects.[1][3] Its mechanism of action in terms of hair growth is still unknown, although multiple potential mechanisms have been implicated.[1]
Minoxidil sulfate is a
bioactivation of minoxidil into minoxidil sulfate is very unusual and is among the only known instances of sulfation producing a more active drug form.[3][4] Normally, sulfation tends to inactivate drugs by reducing their biological activity and increasing their excretion.[3][4]
Minoxidil sulfate is highly unstable in
absorption into the scalp.[5] In any case, a minoxidil sulfate-based topical formulation has been investigated for the treatment of scalp hair loss.[6][5] Additionally, minoxidil-sulfate-based topical formulations appear to be available for medical use in some parts of the world, for instance in Brazil.[5][7]