Dauricine

Source: Wikipedia, the free encyclopedia.
Dauricine
Names
Preferred IUPAC name
(11R,71R)-16,17,76,77-Tetramethoxy-12,72-dimethyl-11,12,13,14,71,72,73,74-octahydro-4-oxa-1,7(1)-diisoquinolina-3(1,3),5(1,4)-dibenzenaheptaphan-34-ol
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard
 100.208.622 Edit this at Wikidata
UNII
  • InChI=1/C38H44N2O6/c1-39-15-13-26-20-35(42-3)37(44-5)22-29(26)31(39)17-24-7-10-28(11-8-24)46-34-19-25(9-12-33(34)41)18-32-30-23-38(45-6)36(43-4)21-27(30)14-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3/t31-,32-/m1/s1
    Key: AQASRZOCERRGBL-ROJLCIKYBP
  • O(c1cc2c(cc1OC)[C@H](N(C)CC2)Cc6ccc(Oc3c(O)ccc(c3)C[C@@H]5c4c(cc(OC)c(OC)c4)CCN5C)cc6)C
Properties
C38H44N2O6
Molar mass 624.778 g·mol−1
Density 1.186 g/mL
Melting point 115 °C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Dauricine is a plant

Bischler-Napieralski reaction to do so.[3] Dauricine has been studied in vitro for its potential to inhibit cancer cell growth[4][5][6][7] and to block cardiac transmembrane Na+, K+, and Ca2+ ion currents.[8]

References

  1. ^ "CHEBI:4331 - dauricine". ChEBI. Retrieved 30 May 2015.
  2. doi:10.1016/S0040-4039(00)71728-X
    .
  3. ISBN 9780080865331
    . Retrieved 30 May 2015.
  4. S2CID 5501319
    .
  5. S2CID 21824941
    .
  6. PMID 19349962
    .
  7. PMID 23199717
    .
  8. PMID 12466045
    .