Amlodipine/benazepril

Source: Wikipedia, the free encyclopedia.

Amlodipine/benazepril
Combination of
AmlodipineCalcium channel blocker
BenazeprilACE inhibitor
Clinical data
Trade namesLotrel
AHFS/Drugs.comProfessional Drug Facts
License data
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
KEGG
CompTox Dashboard (EPA)
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Amlodipine/benazepril, sold under the brand name Lotrel among others, is a

by mouth.[1]

Common side effects include cough, dizziness, and swelling.

low blood pressure.[1] Use in pregnancy is not recommended.[1] Amlodipine works by increasing the size of arteries while benazepril works by decreasing renin-angiotensin-aldosterone system activity.[1]

The combination was approved for medical use in the United States in 1995.

generic medication.[3] In 2021, it was the 150th most commonly prescribed medication in the United States, with more than 3 million prescriptions.[4][5]

Medical uses

It is used to treat

high blood pressure.[1] It is not a first-line treatment.[6]

References

  1. ^ a b c d e f g h i j "Lotrel- amlodipine besylate and benazepril hydrochloride capsule". DailyMed. U.S. National Library of Medicine. Retrieved 20 June 2021.
  2. ^ Cerner Multum. "Amlodipine and benazepril Uses, Side Effects & Warnings". Drugs.com. Retrieved 10 March 2019.
  3. .
  4. ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
  5. ^ "Amlodipine; Benazepril - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
  6. S2CID 23021242
    .