25TFM-NBOMe

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25TFM-NBOMe
Identifiers
  • 2-(4-trifluoromethyl-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine
JSmol)
  • FC(F)(F)c1c(OC)cc(c(OC)c1)CCNCc2ccccc2OC
  • InChI=1S/C19H22F3NO3/c1-24-16-7-5-4-6-14(16)12-23-9-8-13-10-18(26-3)15(19(20,21)22)11-17(13)25-2/h4-7,10-11,23H,8-9,12H2,1-3H3 checkY
  • Key:FBHVTQIAHOTPAM-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

25TFM-NBOMe (also known as NBOMe-2C-TFM, 2C-TFM-NBOMe, and Cimbi-138) is a derivative of the

5-HT2A receptor, though its relative potency is disputed, with some studies finding it to be of lower potency than 25I-NBOMe,[2][3] while others show it to be of similar or higher potency,[4] possibly because of differences in the assay used.[5]
2C-TFM-NB2OMe can be taken to produce psychedelic effects similar to 2C-I-NB2OMe and 2C-D-NB2OMe.

Legality

United Kingdom

This substance is a

Class A drug in the United Kingdom as a result of the N-benzylphenethylamine catch-all clause in the Misuse of Drugs Act 1971.[6]

See also

References

  1. ^ Heim R (2004). Synthese und Pharmakologie potenter 5-HT2A-Rezeptoragonisten mit N-2-Methoxybenzyl-Partialstruktur. Entwicklung eines neuen Struktur-Wirkungskonzepts [Synthesis and pharmacology of potent 5-HT2A receptor agonists with N-2-methoxybenzyl substructure. Development of a new structure-activity relationship] (PhD thesis) (in German).
  2. ^ Silva M (2009). Theoretical study of the interaction of agonists with the 5-HT2A receptor (PhD thesis). Universität Regensburg.
  3. S2CID 3103050
    .
  4. S2CID 12467684
    .
  5. doi:10.13140/RG.2.2.33671.14245
    .
  6. ^ "The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014". UK Statutory Instruments 2014 No. 1106. www.legislation.gov.uk.
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