Tiletamine
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| Pharmacokinetic data | |
| Metabolism | Liver |
| Excretion | Kidneys |
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Tiletamine is a
dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist.[1] It is related chemically to ketamine.[2]
Tiletamine hydrochloride exists as odorless white crystals.
It is used in
ASA score of III or greater and in animals with CNS signs, hyperthyroidism, cardiac disease, pancreatic or renal disease, pregnancy, glaucoma, or penetrating eye injuries.[3]
Society and Culture
Recreational use of telazol has been documented.[8] Animal studies have also shown that tiletamine produces rewarding and reinforcing effects.[9] Products that combine Tiletamine and Zolazepam are classified as Schedule III controlled substances in the United States.[10] Otherwise, as noted by the DEA, tiletamine is unscheduled: “…[R]ules applicable to the scheduling of tiletamine and zolazepam as individual entities are not warranted [or in effect] at this time. Neither tiletamine nor zolazepam, as discrete substances, is perceived to pose a significant threat to the health and general welfare at this time…”[11]
References
- S2CID 41671395.
- ^ CID 26533 from PubChem
- ^ a b "Tiletamine". Drugs.com. Retrieved 5 January 2012.
- PMID 8126757.
- ^ "Tiletamine". Toxnet. U.S. National Library of Medicine. 21 January 2009.
- PMID 14567228.
- PMID 10642872.
- S2CID 21280839.
- S2CID 25425333.
- ^ "Lists of: Scheduling Actions, Controlled Substances, Regulated Chemicals" (PDF). Drug Enforcement Administration. Archived from the original (PDF) on 17 April 2016. Retrieved 5 January 2012.
- ^ "Schedules of Controlled Substances: Placement of Preparations Which Contain Both Tiletamine and Zolazepam into Schedule III" (PDF). Isomer Design. Drug Enforcement Administration. January 21, 1987. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.