Bohlmann–Rahtz pyridine synthesis
Source: Wikipedia, the free encyclopedia.
Bohlmann–Rahtz pyridine synthesis | |
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Named after | Ferdinand Bohlmann Dieter Rahtz |
Reaction type | Ring forming reaction |
Identifiers | |
Organic Chemistry Portal | bohlmann-rahtz-pyridine-synthesis |
In
pyridines in two steps, first a condensation reaction between an enamine and an ethynylketone to form an aminodiene intermediate, which after heat-induced E/Z isomerization undergoes a cyclodehydration to yield 2,3,6-trisubstituted pyridines.[1][2][3][4]
References
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