Bohlmann–Rahtz pyridine synthesis

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Bohlmann–Rahtz pyridine synthesis
Named after Ferdinand Bohlmann
Dieter Rahtz
Reaction type Ring forming reaction
Identifiers
Organic Chemistry Portal bohlmann-rahtz-pyridine-synthesis

In

pyridines in two steps, first a condensation reaction between an enamine and an ethynylketone to form an aminodiene intermediate, which after heat-induced E/Z isomerization undergoes a cyclodehydration to yield 2,3,6-trisubstituted pyridines.[1][2][3][4]

References