Class of DNA-binding proteins that regulate gene transcription
Activating transcription factor, ATF, is a group of
c-Fos.[3] In general, ATFs are known to respond to extracellular signals and this suggests an important role that they have in maintaining homeostasis. Some of these ATFs, such as ATF3, ATF4, and ATF6 are known to play a role in stress responses.[4] Another example of ATFs function would be ATFx that can suppress apoptosis.[5]