bZIP domain
| bZIP transcription factor | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CDD | cd14686 | ||||||||
| Membranome | 235 | ||||||||
| |||||||||
The Basic Leucine Zipper Domain (bZIP domain) is found in many
bZIP transcription factors
bZIP transcription factors are found in all eukaryotes and form one of the largest families of dimerizing TFs.[3] An evolutionary study from 2008 revealed that 4 bZIP genes were encoded by the genome of the most recent common ancestor of all plants.[4] Interactions between bZIP transcription factors are numerous and complex [5][6][3] and play important roles in cancer development[7] in epithelial tissues, steroid hormone synthesis by cells of endocrine tissues,[8] factors affecting reproductive functions,[9] and several other phenomena that affect human health.
bZIP domain containing proteins
- jun heterodimer that forms a transcription factor
- Jun-B transcription factor
- CREB cAMP response element transcription factor
- OPAQUE2 (O2) transcription factor of the 22-kD zein gene that encodes a class of storage proteins in the endosperm of maize (Zea mays) kernels
- NFE2L2 or Nrf2
- Bzip Maf transcription factors
Human proteins containing this domain
; ; ; NFE2; NFE2L2; NFE2L3; SNFT; XBP1References
External links
- bZIP domain entry in the SMART database
- bZIP family at PlantTFDB: Plant Transcription Factor Database
- Plant bZIP transcription factors Archived 2012-03-20 at the Wayback Machine