IRX4
| IRX4 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 5: 1.88 – 1.89 Mb | Chr 13: 73.41 – 73.42 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Iroquois-class homeodomain protein IRX-4, also known as Iroquois homeobox protein 4, is a protein that in humans is encoded by the IRX4 gene.[5][6]
Function
IRX4 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000113430 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021604 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: iroquois homeobox 4".
- PMID 10625552.
Further reading
- Lewis MT, Ross S, Strickland PA, et al. (1999). "Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast". Cell Tissue Res. 296 (3): 549–54. S2CID 37046813.
- Wang GF, Nikovits W, Bao ZZ, Stockdale FE (2001). "Irx4 forms an inhibitory complex with the vitamin D and retinoic X receptors to regulate cardiac chamber-specific slow MyHC3 expression". J. Biol. Chem. 276 (31): 28835–41. PMID 11382777.
- Bayrak F, Kömürcü-Bayrak E, Mutlu B, et al. (2008). "Genetic analysis of the Irx4 gene in hypertrophic cardiomyopathy". Turk Kardiyol Dern Ars. 36 (2): 90–5. PMID 18497553.
- Cirulli ET, Kasperavičiūtė D, Attix DK, et al. (2010). "Common genetic variation and performance on standardized cognitive tests". European Journal of Human Genetics. 18 (7): 815–820. PMID 20125193.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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