4-Chlorophenylisobutylamine

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4-Chlorophenylisobutylamine
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
Identifiers
  • 1-(4-chlorophenyl)butan-2-amine
JSmol)
  • Clc1ccc(cc1)CC(N)CC
  • InChI=1S/C10H14ClN/c1-2-10(12)7-8-3-5-9(11)6-4-8/h3-6,10H,2,7,12H2,1H3 checkY
  • Key:BDZUAWTZJXBMLX-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

4-Chlorophenylisobutylamine (4-CAB, AEPCA), also known as 4-chloro-α-ethylphenethylamine, is an

methyl has been replaced with an ethyl group.[1]

In comparison to PCA, 4-CAB is approximately 2- and 5-fold less

MBDB, it is not abolished[clarification needed], and is actually similar to that of MDMA.[1]

Relative to PCA, 4-CAB is also substantially less effective as a serotonergic neurotoxin.[1] A single 10 mg/kg administration of PCA to rats produces an approximate 80% decrease in serotonin markers as observed 1 week later.[1] In contrast, 11 mg/kg and 22 mg/kg doses of 4-CAB result in only 20% and 50% decreases, respectively.[1] This is once again similar to MDMA which causes a 40-60% reduction with a single 20 mg/kg dose.[2]

See also

References