TC-2216

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TC-2216

Identifiers
IUPAC name 8-pyridin-3-yl-1,8-diazaspiro[4.4]nonane
JSmol)	Interactive image
SMILES N1CCCC1(CC2)CN2c3cnccc3
InChI InChI=1S/C12H17N3/c1-3-11(9-13-6-1)15-8-5-12(10-15)4-2-7-14-12/h1,3,6,9,14H,2,4-5,7-8,10H2 Key:NXIPMBQVNTWEEX-UHFFFAOYSA-N
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TC-2216 is a drug developed by Targacept which acts as a partial agonist at neural nicotinic acetylcholine receptors and was researched for the treatment of anxiety and depression.^[1] It was unsuccessful as a therapeutic but is still used in pharmacological research as an alpha4beta2-selective antagonist.^[2]

References